Prion Disease: Close Encounters Of The Cellular Kind
نویسنده
چکیده
Co-culture of prion-infected cells with uninfected target cells has recently been found to lead to rapid and efficient transmission of infectivity to the target cells by a process that is dependent on direct cell contact.
منابع مشابه
Introducing critical residues in the human prion protein and its Asp 178 Asn mutant by molecular dynamics simulation
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متن کاملگزارش یک مورد بیماری کروتزفلد ژاکوب بدنبال حجامت (گزارش موردی)
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E indications that the infectious agent responsible for scrapie did not contain nucleic acid (1) led to several insightful hypotheses to explain this conundrum (2). Eventually considerable data came to support one of these ideas, dubbed the prion hypothesis, also shown to be applicable to related fatal transmissible spongiform encephalopathies including Creutzfeldt–Jakob and mad cow disease (3)...
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عنوان ژورنال:
- Current Biology
دوره 12 شماره
صفحات -
تاریخ انتشار 2002